Lyme disease, seizures, MS, ALS, Parkinson's, Autism, Alzheimer's, and other chronic conditions, have been shown to have ammonia accumulating in the brain and body. Where the ammonia is accumulating determines the type of symptoms will be created. Each of the above illnesses have been shown by medical researchers to have Lyme spirochetes as a primary cause of the problem.
As the discoverer that Lyme spirochetes cause the accumulation of ammonia it is very validating to me that other scientists and clinicians have confirmed the finding.
Although many people have heard of Leaky Bowel Syndrome (LBS), few have heard of Leaky Brain Syndrome. I coined this term when I became aware of the damaging effects on the blood-brain barrier (BBB) from the accumulation of Lyme-induced ammonia in the brain. Ammonia in the brain is a primary cause of neurological and psychological hypersensitivity.
The ammonia problem occurs not just in the brain, but in any tissue infected with Lyme disease spirochetes. So if it is primary in the joints, then the joints will have excessive amounts of ammonia causing problems. This article will focus of the brain.
Although many people have heard of Leaky Bowel Syndrome (LBS), few have heard of Leaky Brain Syndrome. I coined this term when I became aware of the damaging effects on the blood-brain barrier (BBB) from the accumulation of Lyme-induced ammonia in the brain. Ammonia in the brain is a primary cause of neurological and psychological hypersensitivity.
The ammonia problem occurs not just in the brain, but in any tissue infected with Lyme disease spirochetes. So if it is primary in the joints, then the joints will have excessive amounts of ammonia causing problems. This article will focus of the brain.
Ammonia Pokes Holes In Your Blood-Brain-Barrier (BBB)
If the brain is the central computer of your body, then problems in the brain can cause problems anywhere in your body, mind, and emotions. Ammonia in the brain alters the permeability of the BBB, punching holes in the BBB that enable larger molecules to cross from the bloodstream into the brain, such as common amino-acids, microbes, toxins that normally would not be able to cross the blood-brain-barrier.
When these random molecules touch the brain tissues they set up neuro-inflammation, hyper-reactivity and hypersensitivities to stimuli, such as environmental scents, chemical toxins, mycotoxins, metabolic products, emotions, and even changes in barometric pressure, moon phases, and geopathic stressors. Many people with these issues feel that they suffer from cerebral allergies, but cannot pin any one cause down.
If the brain is the central computer of your body, then problems in the brain can cause problems anywhere in your body, mind, and emotions. Ammonia in the brain alters the permeability of the BBB, punching holes in the BBB that enable larger molecules to cross from the bloodstream into the brain, such as common amino-acids, microbes, toxins that normally would not be able to cross the blood-brain-barrier.
When these random molecules touch the brain tissues they set up neuro-inflammation, hyper-reactivity and hypersensitivities to stimuli, such as environmental scents, chemical toxins, mycotoxins, metabolic products, emotions, and even changes in barometric pressure, moon phases, and geopathic stressors. Many people with these issues feel that they suffer from cerebral allergies, but cannot pin any one cause down.
The Vicious Ammonia-Histamine Cycle
Indeed, the presence of ammonia and the worsening of symptoms can be made worse by the body's production of excessive amounts of histamine and the histamine increases the production of ammonia. This is a vicious cycle of ammonia causing the release of histamine and the histamine causing even more ammonia!
If a person with Lyme disease (LD) is taking a medication that they are allergic to, such as an antibiotic, unfortunately the resulting worsening of symptoms is often thought of as being a Herxheimer reaction from the toxicity of the bacterial die-off substances. Unfortunately, our clinical testing reveals that the person is often suffering from a allergic reaction that is stimulating a histamine release. The histamine release exponentially increases the amount of ammonia in the tissues, and that is indeed why the person is having a dramatic worsening of their symptoms, not from bacterial die-off. Excessive histamine in the body, and Histamine Intolerance are a horrible malady by itself, even without the addition of ammonia!
Complex Illnesses Require Complex Treatments
If a person has Lyme disease AND Histamine Intolerance the chances of profound illness affecting almost every system of the body is almost assured!
If you study both problems, excess ammonia and excess histamine, you can see why the doctors of the Hansa Center for Optimum Health are so unique. Most doctors specialize in a field of medicine. Our doctors specialize in restoring every aspect and adjust every tissue and issue right down to these biochemical nightmares, and even the epigenetic and bioenergetic issues. The chronic illnesses of today are way too complex to be resolved with sledge-hammer drugs.
Indeed, the presence of ammonia and the worsening of symptoms can be made worse by the body's production of excessive amounts of histamine and the histamine increases the production of ammonia. This is a vicious cycle of ammonia causing the release of histamine and the histamine causing even more ammonia!
If a person with Lyme disease (LD) is taking a medication that they are allergic to, such as an antibiotic, unfortunately the resulting worsening of symptoms is often thought of as being a Herxheimer reaction from the toxicity of the bacterial die-off substances. Unfortunately, our clinical testing reveals that the person is often suffering from a allergic reaction that is stimulating a histamine release. The histamine release exponentially increases the amount of ammonia in the tissues, and that is indeed why the person is having a dramatic worsening of their symptoms, not from bacterial die-off. Excessive histamine in the body, and Histamine Intolerance are a horrible malady by itself, even without the addition of ammonia!
Complex Illnesses Require Complex Treatments
If a person has Lyme disease AND Histamine Intolerance the chances of profound illness affecting almost every system of the body is almost assured!
If you study both problems, excess ammonia and excess histamine, you can see why the doctors of the Hansa Center for Optimum Health are so unique. Most doctors specialize in a field of medicine. Our doctors specialize in restoring every aspect and adjust every tissue and issue right down to these biochemical nightmares, and even the epigenetic and bioenergetic issues. The chronic illnesses of today are way too complex to be resolved with sledge-hammer drugs.
The histamine/ammonia cycle affects people even worse if they have key genetic SNP mutations and those who have impaired methylation pathways. "If methylation is low and T cell production is low, then histamine levels tend to be high. Histamine is linked to inflammation, a contributing factors to leaky gut as well as allergies."
The symptoms of these cerebral allergies are unique to what part of the brain is being affected. Ammonia-induced Leaky Brain Syndrome is one of the primary causes of Multiple Chemical Sensitivities, Cognitive dysfunction, Chronic Fatigue Syndrome, MS, ALS, and a myriad of other chronic conditions.
There are only a few ways ammonia can become a problem in the brain. Severe liver disease is a well recognized producer of global or systemic ammonia. No one knew, until I discovered quite unexpectedly, that Lyme spirochetes could cause ammonia to accumulate in localized areas of the brain.
Treating and Detoxifying the Body of Ammonia
While detoxifying and eliminating the excess ammonia from the body can almost immediately improve a persons symptoms, and there are many products that can help the body accomplish this, the cause of the production of ammonia remains as does the damage the ammonia causes in the tissues still needs to be repaired.
In the same way that a screwdriver will not cut wood, antibiotics cannot treat tissue damage, nor can they repair damage to the BBB or the other damaged tissues in your body.
In the same way, simply killing the bacteria and eliminating the ammonia, while good, cannot do more than they do. Your doctor must have many more tools and advanced treatment techniques that focus of restoring the body's ability to heal itself from the inside out and the outside in! This is why I was forced to innovate new ways to test and treat the totality of the body, not just doing pieces and parts doctoring.
How I Discovered Lyme-Induced Ammonia
I first became aware of brain-ammonia problems in the late 1990's while treating a gentleman from England who came to me having been diagnosed with Lyme disease (Neuroborreliosis). Quite surprisingly, my testing revealed Trypanosoma gambiense as his primary microbial challenge. T. gambiense causes African Sleeping Sickness (ASS). Only after subsequent study, in Cecil's Pathology book, did I find that the symptoms of ASS are caused by the neurotoxic effects of ammonia produced in the brain by the microbe. Interestingly, the man said that for years he had told doctors that it felt like someone was pouring ammonia over his brain!
The severe debilitation of this man is what stimulated my discovery of Lyme-induce ammonia. His symptoms reminded me of many of my patients previously diagnosed with extreme Chronic Fatigue, Fibromyalgia, MS, ALS, and Lyme patients.
There are only a few ways ammonia can become a problem in the brain. Severe liver disease is a well recognized producer of global or systemic ammonia. No one knew, until I discovered quite unexpectedly, that Lyme spirochetes could cause ammonia to accumulate in localized areas of the brain.
Treating and Detoxifying the Body of Ammonia
While detoxifying and eliminating the excess ammonia from the body can almost immediately improve a persons symptoms, and there are many products that can help the body accomplish this, the cause of the production of ammonia remains as does the damage the ammonia causes in the tissues still needs to be repaired.
In the same way that a screwdriver will not cut wood, antibiotics cannot treat tissue damage, nor can they repair damage to the BBB or the other damaged tissues in your body.
In the same way, simply killing the bacteria and eliminating the ammonia, while good, cannot do more than they do. Your doctor must have many more tools and advanced treatment techniques that focus of restoring the body's ability to heal itself from the inside out and the outside in! This is why I was forced to innovate new ways to test and treat the totality of the body, not just doing pieces and parts doctoring.
How I Discovered Lyme-Induced Ammonia
I first became aware of brain-ammonia problems in the late 1990's while treating a gentleman from England who came to me having been diagnosed with Lyme disease (Neuroborreliosis). Quite surprisingly, my testing revealed Trypanosoma gambiense as his primary microbial challenge. T. gambiense causes African Sleeping Sickness (ASS). Only after subsequent study, in Cecil's Pathology book, did I find that the symptoms of ASS are caused by the neurotoxic effects of ammonia produced in the brain by the microbe. Interestingly, the man said that for years he had told doctors that it felt like someone was pouring ammonia over his brain!
The severe debilitation of this man is what stimulated my discovery of Lyme-induce ammonia. His symptoms reminded me of many of my patients previously diagnosed with extreme Chronic Fatigue, Fibromyalgia, MS, ALS, and Lyme patients.
I started doing clinical testing for accumulations of ammonia in people with confirmed Lyme disease, and found that all of these people had localized ammonia accumulations primarily in the brain, heart, liver, and jaws caused by the bacteria Borrelia burgdorferi (Bb), the causative agent in Lyme disease. This is no small finding, nor is it easy to correct, although many will tell you of this or that supplement that will rid your body of ammonia. Most of these substances, such as L-ornithine and molybdenum, and various herbs do not seem to be able to clear the ammonia from the brain, or jaws.
How to Test Yourself for Ammonia Accumulation:
There is a Serum Ammonia and a urine ammonia test that can be performed by your doctor, however due to the fact that the Lyme-induced ammonia is not a systemic problem, but is in localized areas, the lab tests may not be as reliable to detect the presence of ammonia.
I am pleased to say that over the last decade my findings have now been confirmed by many other doctors and scientists. (Ammonia)
It would seem that Bb release ammonia, which is converted to glutamine, by way of the glutamine synthetase pathways, leading to localized swelling of astrocytes (brain cells). This ammonia-induced glutamine accumulation may cause dysfunction of astrocytes that leads to impairment of vascular reactivity other than through a decrease in arginine availability for NOS leading to increased production of nitric oxide (Toshiki 2000).
It has been reported that many neurological problems are caused by either congenital causes in SNP mutations, or acquired hyper-ammonemia from various infectious agents or liver disease (Albrecht 1998).
It would seem that Bb release ammonia, which is converted to glutamine, by way of the glutamine synthetase pathways, leading to localized swelling of astrocytes (brain cells). This ammonia-induced glutamine accumulation may cause dysfunction of astrocytes that leads to impairment of vascular reactivity other than through a decrease in arginine availability for NOS leading to increased production of nitric oxide (Toshiki 2000).
It has been reported that many neurological problems are caused by either congenital causes in SNP mutations, or acquired hyper-ammonemia from various infectious agents or liver disease (Albrecht 1998).
Many of my patient previously diagnosed with LD have reported that brain MRI's found MS-type plaques on their brain. These plaques are likely from the increased ammonia from the Borrelia burgdorferi bacteria.
All of the ammonia-related pathological changes predispose these individuals to cerebral allergies, due to alterations in the blood brain barrier, subsequently allowing larger molecules, such as common dietary amino acids, to pass through to the brain. Neurotransmitter receptors and function is impaired and possibly the most common symptom – altered brain energy metabolism leading to cognitive brain dysfunctions, the total fatigue of the mind when forced to read, talk, or think for extended periods.
Direct Resonance Testing (DRT) was used to test for the presence of ammonia in the brain, heart, and liver of over 2000 previously diagnosed LD, MS, CFS, ALS, and other chronically ill patients; all patients were positive for ammonia over these areas.
All of the ammonia-related pathological changes predispose these individuals to cerebral allergies, due to alterations in the blood brain barrier, subsequently allowing larger molecules, such as common dietary amino acids, to pass through to the brain. Neurotransmitter receptors and function is impaired and possibly the most common symptom – altered brain energy metabolism leading to cognitive brain dysfunctions, the total fatigue of the mind when forced to read, talk, or think for extended periods.
Direct Resonance Testing (DRT) was used to test for the presence of ammonia in the brain, heart, and liver of over 2000 previously diagnosed LD, MS, CFS, ALS, and other chronically ill patients; all patients were positive for ammonia over these areas.
Many other doctors have confirmed this finding using the Direct Resonance Testing. A Direct Resonance Test functions based upon the fact that every bend, rotation, or atomic bond of a given molecular structure, such as NH3, has a certain resonant frequency (Oschman 2000). When two substances similar molecular frequency come in close proximity to each other they will tend to vibrate "sympathetically" through harmonic resonance. (Allen and Cross 1963, Sauer 1995)
How to Test Yourself for Ammonia Accumulation:
There is a Serum Ammonia and a urine ammonia test that can be performed by your doctor, however due to the fact that the Lyme-induced ammonia is not a systemic problem, but is in localized areas, the lab tests may not be as reliable to detect the presence of ammonia.
Direct Resonance Testing:
To perform a direct resonance test the doctor will need a vial of pure ammonia. A muscle strength challenge should be performed to identify a strong muscle, preferably using the deltoid muscle with the patient’s thumb pointing towards the feet. The muscle should “lock” or immediately be be strong when challenged, without being spongy. The doctor should use only the amount of force necessary to feel that the muscle being tested engages without being spongy. Once a good strong muscle has been identified, hold the vial of ammonia over various areas of the brain, testing to see if the previously strong muscle goes weak when the ammonia is held over any area. Due to the temporary neuromuscular interference caused by the harmonic resonance of ammonia in the vial with the ammonia present in the brain, the strong muscle will go weak. If the test is positive all over the body then there is more than just Lyme infection going on, since LD-induce ammonia accumulations seem to only affect the liver, heart, brain, and jaws.
For solutions to help the body eliminate ammonia read this link.
For solutions to help the body eliminate excessive histamine read this link.
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For over 20 years the Hansa Center for Optimum Health, in Wichita, Kansas has specialized in the restoration of health for people with previously unresponsive and chronic illnesses of virtually all types. Over 85% of people come from other states and countries. If you have done everything you and your doctor know to do and are still struggling, contact our wonderful Patient Care Coordinator, Kara, at patientcare@hansacenter.com, for information on the exciting new treatments we have developed at the Hansa Center for Optimum Health. For additional info, visit our website at www.HansaCenter.com.
This article is for educational purposes. Before implementing any supplements/remedies always consult with your healthcare professional. Due to the complexity of the human condition there remains the possibility of symptoms getting worse. Again, discuss the ideas presented here with your health care professional before beginning, and stop, or get support, if your condition worsens. This information is not intended to treat, cure, diagnose, or mitigate any disease or illness, and has not been evaluated by the FDA. The Hansa Center does not treat named diseases, but seeks to restore the body's optimum structural and functional integrity so that the body can rapidly heal itself.
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